Hair Loss in Denizli: PRP or Mesotherapy?

When someone with hair loss comes to an appointment, the question on their mind is usually: "Should I have PRP or mesotherapy?" Yet the two treatments are not rivals, and neither removes the cause of hair loss on its own. What decides which one will help is, first of all, the type of hair loss. That is why, as part of hair loss treatment in Denizli, we decide on PRP or mesotherapy only once a diagnosis has been made.

The comparison below shows what each method does differently and when one comes to the fore. The final shape of the plan for your scalp depends on what we find at the examination.

What Is the Difference Between PRP and Hair Mesotherapy?

The key difference is where the substance given to the scalp comes from. With PRP nothing comes from outside: blood taken from the arm is separated in a centrifuge and the platelet-rich plasma is returned to the hair follicles. The growth factors carried by platelets stimulate repair around weakened follicles. Hair mesotherapy uses a ready-made mixture of substances the follicles need, such as vitamins, minerals and amino acids; the aim is to nourish the follicle directly.

The session numbers in the table are a starting plan. We may change the length and spacing of the course according to how severe the hair loss is and how you respond at the first review.

Why Must the Type of Hair Loss Be Identified First?

Because very different causes can sit behind the same complaint. If iron deficiency, an underactive thyroid or a side effect of medication is causing the hair loss, no treatment applied to the scalp will correct that deficiency. The cause is corrected first; PRP or mesotherapy comes second, if needed.

At the examination we take your history, look at your scalp and examine the follicles under magnification with trichoscopy. Choosing a method before the causes and diagnosis of hair loss are clear can mean spending time and effort on sessions that bring no result. If the examination does not settle the diagnosis, especially when inflammation around the follicles is suspected, a small scalp biopsy may be needed.

Which Hair Loss Calls for PRP, and Which for Mesotherapy?

Male and female pattern hair loss

With a genetic tendency, the follicles become a little thinner with each cycle. Medication is the main treatment here; PRP and mesotherapy are supportive steps added to it. Studies suggest PRP can contribute to hair density in genetic thinning, so in this group PRP is one of the leading options. Response varies from person to person; follicles that have thinned but are still present respond better than areas where the follicle has been lost entirely.

Hair loss after stress, illness or childbirth

This pattern usually recovers on its own once the trigger has passed. The first step is to check for a deficiency that keeps the shedding going. If shedding lasts longer than expected or leaves noticeable thinning, hair mesotherapy can be planned to nourish the follicles.

Alopecia areata

In alopecia areata, treatment is based on local and, if needed, systemic treatments chosen according to the size of the area. Mesotherapy can be part of this plan, but it does not replace the local treatment.

Conditions that cause permanent hair loss

In scarring hair conditions the follicle has been destroyed and the lost area does not grow back. The priority is to stop the inflammation; PRP and mesotherapy are not considered the main treatment.

Can PRP and Hair Mesotherapy Be Used Together?

Yes. Because the two methods work differently, some patients can have both in sequence within the same treatment plan. For example, someone with genetic thinning who has also been through a stressful period may benefit from a plan that both nourishes the follicle and stimulates repair, alongside medication. We decide which comes first and at what intervals according to how the hair loss progresses.

Microneedling with Dermapen, which opens micro-channels in the scalp, can be added to increase the penetration of the substances used in either method. We do not use Dermapen alone for hair; we combine it with PRP or mesotherapy.

When Do PRP and Mesotherapy Show Results?

With both methods, results are assessed over months rather than weeks, because it takes time for a follicle to produce a new, thick hair. The first change people usually notice is less shedding. We assess changes in hair thickness and density at the review after the course, comparing photographs taken in the same light and from the same angle.

In terms of sessions, PRP runs with fewer sessions at longer intervals. Mesotherapy sessions are more frequent and more numerous. With both, maintenance or top-up sessions may be needed after the course if the cause of the hair loss continues.

Who Is PRP or Mesotherapy Not Suitable For?

The situations in which each method is unsuitable differ and can decide the choice:

• PRP: a low platelet count, clotting disorders, blood thinners, ongoing cancer treatment and pregnancy
• Hair mesotherapy: pregnancy, an active scalp infection, inflamed spots or an open wound, and a known allergy to the ingredients of the mixture

If there is flaking, itching or redness on the scalp, before either treatment we check whether it is due to a condition such as seborrhoeic dermatitis or psoriasis. A treatment given before the scalp has healed has limited effect.

Which Questions Guide Our Choice?

1. What type of hair loss is it: genetic thinning, shedding after a trigger, or alopecia areata?
2. Is there a deficiency or hormonal problem keeping the hair loss going?
3. Are the follicles still present, or are there areas where they have been lost?
4. Is there a blood condition or medication that rules out PRP?
5. Does the session frequency fit your daily life and schedule?

The answers sometimes point to PRP alone, sometimes to mesotherapy alone and sometimes to a plan that uses both. In some patients we find that neither is needed and that medication with follow-up is enough.

PRP and Mesotherapy Planning for Hair in Denizli

At our Denizli clinic, Dr. Tuba Çelebi Kayhan carries out the hair loss examination, the treatment plan and the reviews. After the examination we explain why a method has been chosen, how many sessions it will take and when the result will be assessed. You can read how the plasma is prepared under PRP treatment for hair, and how a session runs under hair mesotherapy sessions. To book an appointment, please call us.